Vitamin D/vitamin D receptor protects intestinal barrier against colitis by positively regulating Notch pathway

Vitamin D/vitamin D receptor protects intestinal barrier against colitis by positively regulating Notch pathway

ObjectiveVitamin D/Vitamin D receptor (VD/VDR) signaling and the Notch pathway are involved in intestinal barrier restoration in colitis; however, their relationship and underlying mechanism are largely unknown. Therefore, this study aimed to investigate the role and mechanism of VD/VDR and the Notc...

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Bibliografske podrobnosti
Main Authors: Yanni Li, Yaoyu Guo, Chong Geng, Shuailing Song, Wenjuan Yang, Xiao Li, Chunhui Wang
Format: Article
Jezik:English
Izdano: Frontiers Media S.A. 2024-07-01
Serija:Frontiers in Pharmacology
Teme:
tight junction
intestinal barrier
vitamin D
vitamin D receptor (VDR)
ulcerative colitis
Notch pathway
Online dostop:https://www.frontiersin.org/articles/10.3389/fphar.2024.1421577/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2024.1421577/full

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