Vitamin D/vitamin D receptor protects intestinal barrier against colitis by positively regulating Notch pathway

Vitamin D/vitamin D receptor protects intestinal barrier against colitis by positively regulating Notch pathway

ObjectiveVitamin D/Vitamin D receptor (VD/VDR) signaling and the Notch pathway are involved in intestinal barrier restoration in colitis; however, their relationship and underlying mechanism are largely unknown. Therefore, this study aimed to investigate the role and mechanism of VD/VDR and the Notc...

Full description

Bibliographic Details
Main Authors: Yanni Li, Yaoyu Guo, Chong Geng, Shuailing Song, Wenjuan Yang, Xiao Li, Chunhui Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-07-01
Series:Frontiers in Pharmacology
Subjects:
tight junction
intestinal barrier
vitamin D
vitamin D receptor (VDR)
ulcerative colitis
Notch pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1421577/full

Similar Items

Similar Items