The investigation of 2D monolayers as potential chelation agents in Alzheimer’s disease

In this study, we conducted density functional theory calculations comparing the binding energy of the copper-amyloid-β complex to the binding energies of potential chelation materials. We used the first-coordination sphere of the truncated high-pH amyloid-β protein subject to computational limits....

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Bibliographic Details
Main Authors: N. Pavuluru, X. Luo
Format: Article
Language:English
Published: AIP Publishing LLC 2019-12-01
Series:AIP Advances
Online Access:http://dx.doi.org/10.1063/1.5125123