Quantitative iron–neuromelanin MRI associates with motor severity in Parkinson's disease and matches radiological disease classification

Quantitative iron–neuromelanin MRI associates with motor severity in Parkinson's disease and matches radiological disease classification

BackgroundNeuromelanin- and iron-sensitive MRI studies in Parkinson's disease (PD) are limited by small sample sizes and lack detailed clinical correlation. In a large case–control PD cohort, we evaluated the diagnostic accuracy of quantitative iron–neuromelanin MRI parameters from the substant...

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Bibliographic Details
Main Authors: Septian Hartono, Robert Chun Chen, Thomas Welton, An Sen Tan, Weiling Lee, Peik Yen Teh, Celeste Chen, Wenlu Hou, Wei Ping Tham, Ee Wei Lim, Kumar M. Prakash, Yao-Chia Shih, Kuan Jin Lee, Louis C. S. Tan, Eng King Tan, Ling Ling Chan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Aging Neuroscience
Subjects:
Parkinson's disease
MRI
substantia nigra
classification
comparative study
correlation analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1287917/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2023.1287917/full

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