Ovarian Cancer-Associated Ascites Have High Proportions of Cytokine-Responsive CD56bright NK Cells

Ovarian Cancer-Associated Ascites Have High Proportions of Cytokine-Responsive CD56bright NK Cells

Ovarian cancer is the most lethal gynecological malignancy, with serous histotype as the most prevalent epithelial ovarian cancer (EOC). Peritoneal ascites is a frequent comorbidity in advanced EOC. EOC-associated ascites provide a reliable sampling source for studying lymphocytes directly from tumo...

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Bibliographic Details
Main Authors: Cláudia Rodrigues Tonetti, Caroline Natânia de Souza-Araújo, Adriana Yoshida, Rodrigo Fernandes da Silva, Paulo César Martins Alves, Taís Nitsch Mazzola, Sophie Derchain, Luís Gustavo Romani Fernandes, Fernando Guimarães
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
cytotoxic lymphocytes
STAT5
pS6
inhibitory checkpoint receptor
tumor microenvironment
ectonucleotidases
Online Access:https://www.mdpi.com/2073-4409/10/7/1702

Internet

https://www.mdpi.com/2073-4409/10/7/1702

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