Using phage and yeast display to select hundreds of monoclonal antibodies: application to antigen 85, a tuberculosis biomarker.

BACKGROUND: Current diagnostic methods for tuberculosis (TB), a major global health challenge that kills nearly two million people annually, are time-consuming and inadequate. During infection a number of bacterial molecules that play a role in the infective process are released and have been propos...

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Bibliographic Details
Main Authors: Fortunato Ferrara, Leslie A Naranjo, Sandeep Kumar, Tiziano Gaiotto, Harshini Mukundan, Basil Swanson, Andrew R M Bradbury
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3498134?pdf=render