Anti-Apoptotic Gene Delivery with cyclo-(d-Trp-Tyr) Peptide Nanotube via Eye Drop Following Corneal Epithelial Debridement

Corneal keratocyte apoptosis triggered by cornel debridement is one mechanism of corneal disorders. In this study, the feasibility of cyclo-(d-Trp-Tyr) peptide nanotubes (PNTs) as carriers of caspase 3 silence shRNA delivery was assessed. A model of epithelial injury by epithelial debridement was ap...

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Bibliographic Details
Main Authors: Yu-Hsing Lee, Shwu-Fen Chang, Jiahorng Liaw
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Pharmaceutics
Subjects:
Online Access:http://www.mdpi.com/1999-4923/7/3/122