Temporal dynamics of Candida albicans morphogenesis and gene expression reveals distinctions between in vitro and in vivo filamentation

ABSTRACTCandida albicans is a common human fungal pathogen that is also a commensal of the oral cavity and gastrointestinal tract. C. albicans pathogenesis is linked to its transition from budding yeast to filamentous morphologies including hyphae and pseudohyphae. The centrality of this virulence t...

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Bibliographic Details
Main Authors: Rohan S. Wakade, Melanie Wellington, Damian J. Krysan
Format: Article
Language:English
Published: American Society for Microbiology 2024-04-01
Series:mSphere
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/msphere.00110-24