Prophylactic and therapeutic potential of magnolol-loaded PLGA-PEG nanoparticles in a chronic murine model of allergic asthma

Magnolol is a chemically defined and active polyphenol extracted from magnolia plants possessing anti-allergic activity, but its low solubility and rapid metabolism dramatically hinder its clinical application. To improve the therapeutic effects, magnolol-encapsulated polymeric poly (DL-lactide-co-g...

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Bibliographic Details
Main Authors: Junyi Wang, Mo Xian, Hui Cao, Lei Wu, Libo Zhou, Yihe Ma, Long Fan, Lin Lin, Guoping Li, Qinmiao Huang, Shau-Ku Huang, Xiaojun Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1182080/full