Autoimmune HLA Alleles and Neoepitope Presentation Predict Post-Allogenic Transplant Relapse

Autoimmune HLA Alleles and Neoepitope Presentation Predict Post-Allogenic Transplant Relapse

Introduction: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) can cure patients with high-risk myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). However, many patients relapse or develop debilitating graft-versus-host disease. Transplant restores T-cell reactivity agai...

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Bibliographic Details
Main Authors: Andrea Castro, Aaron M. Goodman, Zachary Rane, James V. Talwar, Garrett M. Frampton, Gerald P. Morris, Scott M. Lippman, Xinlian Zhang, Razelle Kurzrock, Hannah Carter
Format: Article
Language:English
Published: Innovative Healthcare Institute 2023-08-01
Series:Journal of Immunotherapy and Precision Oncology
Subjects:
allo-hsct
hla genotype
neoantigen
relapse
acute myeloid leukemia
Online Access:https://jipo.org/doi/pdf/10.36401/JIPO-22-19

Internet

https://jipo.org/doi/pdf/10.36401/JIPO-22-19

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