Glutathione metabolism in Candida albicans resistant strains to fluconazole and micafungin.

Currently available therapies for candidiasis are based on antifungal drugs belonging to azole and echinocandin families that interfere with different aspects of fungal metabolism. These drugs, beyond their specific effects, elicit also a cellular stress including an unbalance of redox state that is...

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Bibliographic Details
Main Authors: Bruno Maras, Letizia Angiolella, Giuseppina Mignogna, Elisabetta Vavala, Alberto Macone, Marisa Colone, Giuseppina Pitari, Annarita Stringaro, Silvestro Dupré, Anna Teresa Palamara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4045664?pdf=render