Chitosan oligosaccharide alleviates renal fibrosis through reducing oxidative stress damage and regulating TGF-β1/Smads pathway

Abstract Renal fibrosis (RF) is the common pathway for a variety of chronic kidney diseases that progress to end-stage renal disease. Chitosan oligosaccharide (COS) has been identified as possessing many health functions. However, it is not clear whether COS can prevent RF. The purpose of this paper...

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Bibliographic Details
Main Authors: Jun Wu, Yingtao Xu, Zikai Geng, Jianqing Zhou, Qingping Xiong, Zhimeng Xu, Hailun Li, Yun Han
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-20719-1