Modulation of GPR133 (ADGRD1) signaling by its intracellular interaction partner extended synaptotagmin 1

Modulation of GPR133 (ADGRD1) signaling by its intracellular interaction partner extended synaptotagmin 1

Summary: GPR133 (ADGRD1) is an adhesion G-protein-coupled receptor that signals through Gαs/cyclic AMP (cAMP) and is required for the growth of glioblastoma (GBM), an aggressive brain malignancy. The regulation of GPR133 signaling is incompletely understood. Here, we use proximity biotinylation prot...

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Bibliographic Details
Main Authors: Gabriele Stephan, Sara Haddock, Shuai Wang, Hediye Erdjument-Bromage, Wenke Liu, Niklas Ravn-Boess, Joshua D. Frenster, Devin Bready, Julia Cai, Rebecca Ronnen, Jonathan Sabio-Ortiz, David Fenyo, Thomas A. Neubert, Dimitris G. Placantonakis
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Cell Reports
Subjects:
CP: Cell biology
CP: Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724005576

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http://www.sciencedirect.com/science/article/pii/S2211124724005576

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