Radiosynthesis and Bioevaluation of <sup>99m</sup>Tc-Labeled Isocyanide Ubiquicidin 29-41 Derivatives as Potential Agents for Bacterial Infection Imaging

Radiosynthesis and Bioevaluation of <sup>99m</sup>Tc-Labeled Isocyanide Ubiquicidin 29-41 Derivatives as Potential Agents for Bacterial Infection Imaging

To develop a novel <sup>99m</sup>Tc-labeled ubiquicidin 29-41 derivative for bacterial infection single-photon emission computed tomography (SPECT) imaging with improved target-to-nontarget ratio and lower nontarget organ uptake, a series of isocyanide ubiquicidin 29-41 derivatives (CNnU...

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Bibliographic Details
Main Authors: Yuhao Jiang, Peiwen Han, Guangxing Yin, Qianna Wang, Junhong Feng, Qing Ruan, Di Xiao, Junbo Zhang
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
<sup>99m</sup>Tc
isocyanide
ubiquicidin 29-41
bacterial infection imaging
Online Access:https://www.mdpi.com/1422-0067/25/2/1045

Internet

https://www.mdpi.com/1422-0067/25/2/1045

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