γδ T cell-mediated cytotoxicity against patient-derived healthy and cancer cervical organoids

γδ T cell-mediated cytotoxicity against patient-derived healthy and cancer cervical organoids

Cervical cancer is a leading cause of death among women globally, primarily driven by high-risk papillomaviruses. However, the effectiveness of chemotherapy is limited, underscoring the potential of personalized immunotherapies. Patient-derived organoids, which possess cellular heterogeneity, proper...

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Bibliographic Details
Main Authors: Junxue Dong, David Holthaus, Christian Peters, Stefanie Koster, Marzieh Ehsani, Alvaro Quevedo-Olmos, Hilmar Berger, Michal Zarobkiewicz, Mandy Mangler, Rajendra Kumar Gurumurthy, Nina Hedemann, Cindrilla Chumduri, Dieter Kabelitz, Thomas F. Meyer
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
cervical cancer
human papillomavirus
ectocervix
organoids
immunotherapy
γδ T cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1281646/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1281646/full

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