Unleashing endogenous TNF-alpha as a cancer immunotherapeutic
Abstract Tumor necrosis factor (TNF)-alpha was originally identified in the 1970s as the serum mediator of innate immunity capable of inducing hemorrhagic necrosis in tumors. Today, a wide spectrum of biological activities have been attributed to this molecule, and clinical translation has mainly oc...
Κύριοι συγγραφείς: | , , , , , , |
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Μορφή: | Άρθρο |
Γλώσσα: | English |
Έκδοση: |
BMC
2018-08-01
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Σειρά: | Journal of Translational Medicine |
Θέματα: | |
Διαθέσιμο Online: | http://link.springer.com/article/10.1186/s12967-018-1611-7 |