Transcriptome analysis reveals organ-specific effects of 2-deoxyglucose treatment in healthy mice.

Transcriptome analysis reveals organ-specific effects of 2-deoxyglucose treatment in healthy mice.

<h4>Objective</h4>Glycolytic inhibition via 2-deoxy-D-glucose (2DG) has potential therapeutic benefits for a range of diseases, including cancer, epilepsy, systemic lupus erythematosus (SLE), and rheumatoid arthritis (RA), and COVID-19, but the systemic effects of 2DG on gene function ac...

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Bibliographic Details
Main Authors: Ann E Wells, John J Wilson, Sarah E Heuer, John D Sears, Jian Wei, Raghav Pandey, Mauro W Costa, Catherine C Kaczorowski, Derry C Roopenian, Chih-Hao Chang, Gregory W Carter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0299595&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0299595&type=printable

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