Drug Discovery Targeting Post-Translational Modifications in Response to DNA Damages Induced by Space Radiation

Drug Discovery Targeting Post-Translational Modifications in Response to DNA Damages Induced by Space Radiation

DNA damage in astronauts induced by cosmic radiation poses a major barrier to human space exploration. Cellular responses and repair of the most lethal DNA double-strand breaks (DSBs) are crucial for genomic integrity and cell survival. Post-translational modifications (PTMs), including phosphorylat...

Full description

Bibliographic Details
Main Authors: Dafei Xie, Qi Huang, Pingkun Zhou
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
radiation protection
space radiation
DSB
post-translational modification
drug target
drug discovery
Online Access:https://www.mdpi.com/1422-0067/24/8/7656

Internet

https://www.mdpi.com/1422-0067/24/8/7656

Similar Items