A mutual regulatory loop between miR-155 and SOCS1 influences renal inflammation and diabetic kidney disease

A mutual regulatory loop between miR-155 and SOCS1 influences renal inflammation and diabetic kidney disease

Diabetic kidney disease (DKD) is a common microvascular complication of diabetes, a global health issue. Hyperglycemia, in concert with cytokines, activates the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway to induce inflammation and oxidative stress contributing...

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Bibliographic Details
Main Authors: Ignacio Prieto, María Kavanagh, Luna Jimenez-Castilla, Marisa Pardines, Iolanda Lazaro, Isabel Herrero del Real, Monica Flores-Muñoz, Jesus Egido, Oscar Lopez-Franco, Carmen Gomez-Guerrero
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
MT: Non-coding RNAs: diabetes
renal inflammation
diabetic kidney disease
fibrosis
microRNA
signal transduction
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253123002597

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http://www.sciencedirect.com/science/article/pii/S2162253123002597

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