N-acetylcysteine Provides Cytoprotection in Murine Oligodendrocytes through Heme Oxygenase-1 Activity

Oligodendrocytic injury by oxidative stress can lead to demyelination, contributing to neurodegeneration. We investigated the mechanisms by which an antioxidant, N-acetylcysteine (NAC), reduces oxidative stress in murine oligodendrocytes. We used normal 158N and mutant 158JP cells with endogenously...

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Бібліографічні деталі
Автори: Jie Zhou, Marcia R. Terluk, Lisa Basso, Usha R. Mishra, Paul J. Orchard, James C. Cloyd, Henning Schröder, Reena V. Kartha
Формат: Стаття
Мова:English
Опубліковано: MDPI AG 2020-07-01
Серія:Biomedicines
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Онлайн доступ:https://www.mdpi.com/2227-9059/8/8/240