Epigenetic Silencing of Tumor Suppressor lncRNA <i>NKILA</i>: Implication on NF-κB Signaling in Non-Hodgkin’s Lymphoma

Epigenetic Silencing of Tumor Suppressor lncRNA <i>NKILA</i>: Implication on NF-κB Signaling in Non-Hodgkin’s Lymphoma

The long non-coding RNA (lncRNA) <i>NKILA, </i>localized to 20q13.31, is a negative regulator of NF-κB signaling implicated in carcinogenesis. As a CpG island is embedded in the promoter region of <i>NKILA</i>, it is hypothesized as a tumor suppressor lncRNA silenced by promo...

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Bibliographic Details
Main Authors: Min-Yue Zhang, George Calin, Ming-Dan Deng, Rex K. H. Au-Yeung, Lu-Qian Wang, Chor-Sang Chim
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Genes
Subjects:
DNA methylation
<i>NKILA</i>
non-Hodgkin’s lymphoma
tumor suppressor
NF-κB signaling
Online Access:https://www.mdpi.com/2073-4425/13/1/128

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https://www.mdpi.com/2073-4425/13/1/128

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