Sequence-Dependent Correlated Segments in the Intrinsically Disordered Region of ChiZ

Sequence-Dependent Correlated Segments in the Intrinsically Disordered Region of ChiZ

How sequences of intrinsically disordered proteins (IDPs) code for their conformational dynamics is poorly understood. Here, we combined NMR spectroscopy, small-angle X-ray scattering (SAXS), and molecular dynamics (MD) simulations to characterize the conformations and dynamics of ChiZ1-64. MD simul...

Full description

Bibliographic Details
Main Authors: Alan Hicks, Cristian A. Escobar, Timothy A. Cross, Huan-Xiang Zhou
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Biomolecules
Subjects:
correlated segment
conformational dynamics
intrinsically disordered protein
molecular dynamics
nuclear magnetic resonance (NMR)
protein conformation
Online Access:https://www.mdpi.com/2218-273X/10/6/946

Internet

https://www.mdpi.com/2218-273X/10/6/946

Similar Items