Targeting Host Glycolysis as a Strategy for Antimalarial Development

Targeting Host Glycolysis as a Strategy for Antimalarial Development

Glycolysis controls cellular energy, redox balance, and biosynthesis. Antiglycolytic therapies are under investigation for treatment of obesity, cancer, aging, autoimmunity, and microbial diseases. Interrupting glycolysis is highly valued as a therapeutic strategy, because glycolytic disruption is g...

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Bibliographic Details
Main Authors: Andrew J. Jezewski, Yu-Hsi Lin, Julie A. Reisz, Rachel Culp-Hill, Yasaman Barekatain, Victoria C. Yan, Angelo D’Alessandro, Florian L. Muller, Audrey R. Odom John
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Plasmodium
antimalarial
red blood cells
erythrocyte
enolase
glycolysis
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.730413/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2021.730413/full

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