Antagonism of Estrogen Receptor α-Driven Transcription Mediated by AP-1 in Breast Cancer Therapy

Antagonism of Estrogen Receptor α-Driven Transcription Mediated by AP-1 in Breast Cancer Therapy

The evolution of breast cancers results from the emergence of epithelial cell subpopulations containing variant Estrogen Receptor α which is able to bypass conventional treatments aimed at antagonizing the activity of this tumor-promoting receptor. The present investigation concerns a few estradiol...

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Bibliographic Details
Main Author: Guy Leclercq
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Endocrines
Subjects:
ligand
conformation change
temperature
breast cancer
endocrine therapy
drug fluorination
Online Access:https://www.mdpi.com/2673-396X/5/1/7

Internet

https://www.mdpi.com/2673-396X/5/1/7

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