Modeling and Simulation of a miRNA Regulatory Network of the PTEN Gene

Modeling and Simulation of a miRNA Regulatory Network of the PTEN Gene

The PTEN onco-suppressor gene is likely to play an important role in the onset of brain cancer, namely glioblastoma multiforme. Consequently, the PTEN regulatory network, involving microRNAs and competitive endogenous RNAs, becomes a crucial tool for understanding the mechanism related to low levels...

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Bibliographic Details
Main Authors: Gionmattia Carancini, Margherita Carletti, Giulia Spaletta
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Mathematics
Subjects:
numerical modeling
ordinary differential equations
LSODA method
stoichiometric matrix
propensity function
PTEN onco-suppressor gene
Online Access:https://www.mdpi.com/2227-7390/9/15/1803

Internet

https://www.mdpi.com/2227-7390/9/15/1803

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