Unusual Resistance Mechanisms in a Case of ROS1-Rearranged NSCLC: A Case Report

Unusual Resistance Mechanisms in a Case of ROS1-Rearranged NSCLC: A Case Report

The unprecedented growth of the high-throughput next-generation sequencing has facilitated the identification of rare oncogene fusions such as ROS1 for NSCLC. ROS1 rearrangement has been observed in only 2% of cases of NSCLC and has been successfully targeted using various tyrosine kinase inhibitors...

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Bibliographic Details
Main Authors: Ullas Batra, MD, Shrinidhi Nathany, MD, Mansi Sharma, MD, Sakshi Mattoo, MSc, Joslia T. Jose, MTech, Anurag Mehta, MD
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:JTO Clinical and Research Reports
Subjects:
ROS1
Crizotinib
Non–small cell lung cancer
Case report
Online Access:http://www.sciencedirect.com/science/article/pii/S266636432200011X

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http://www.sciencedirect.com/science/article/pii/S266636432200011X

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