Comprehensive Molecular Evaluation of HNF-1 Alpha, miR-27a, and miR-146 Gene Variants and Their Link with Predisposition and Progression in Type 2 Diabetes Patients

Comprehensive Molecular Evaluation of HNF-1 Alpha, miR-27a, and miR-146 Gene Variants and Their Link with Predisposition and Progression in Type 2 Diabetes Patients

Background: Type 2 diabetes (T2D) is a metabolic condition induced by insulin resistance and pancreatic beta cell dysfunction. MicroRNAs (miRNAs) have biological significance because they regulate processes such as the molecular signaling pathways involved in the pathophysiology of diabetes mellitus...

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Bibliographic Details
Main Authors: Rashid Mir, Imadeldin Elfaki, M. E. Elangeeb, Mamdoh S. Moawadh, Faris Jamal Tayeb, Jameel Barnawi, Ibrahim Altedlawi Albalawi, Amnah A. Alharbi, Marwan H. Alhelali, Basim S. O. Alsaedi
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Journal of Personalized Medicine
Subjects:
single-nucleotide variations (SNVs)
Amplification Refractory Mutation System PCR (ARMS-PCR)
microRNAs
miR-27a rs895819 SNV
miR-146 rs2910164
hepatocytes nuclear factor-1 alpha (HNF-1 alpha)
Online Access:https://www.mdpi.com/2075-4426/13/8/1270

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https://www.mdpi.com/2075-4426/13/8/1270

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