JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin

Epidermal homeostasis is maintained by the activity of stem cells. Here, the authors show that deficiency of the transcription factor JunB leads to altered Notch signaling in stem cells, resulting in a cell fate switch and de novo formation of aberrant sebaceous glands, altered epidermal differentia...

Full description

Bibliographic Details
Main Authors: Karmveer Singh, Emanuela Camera, Linda Krug, Abhijit Basu, Rajeev Kumar Pandey, Saira Munir, Meinhard Wlaschek, Stefan Kochanek, Marina Schorpp-Kistner, Mauro Picardo, Peter Angel, Catherin Niemann, Pallab Maity, Karin Scharffetter-Kochanek
Format: Article
Language:English
Published: Nature Portfolio 2018-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-05726-z