Conserved charged amino acid residues in the extracellular region of sodium/iodide symporter are critical for iodide transport activity

<p>Abstract</p> <p>Background</p> <p>Sodium/iodide symporter (NIS) mediates the active transport and accumulation of iodide from the blood into the thyroid gland. His-226 located in the extracellular region of NIS has been demonstrated to be critical for iodide transpor...

Full description

Bibliographic Details
Main Authors: Liang Ji-An, Wu Shih-Lu, Kao Chia-Hung, Ho Tin-Yun, Li Chia-Cheng, Hsiang Chien-Yun
Format: Article
Language:English
Published: BMC 2010-11-01
Series:Journal of Biomedical Science
Online Access:http://www.jbiomedsci.com/content/17/1/89