The AMA1-RON complex drives Plasmodium sporozoite invasion in the mosquito and mammalian hosts.

The AMA1-RON complex drives Plasmodium sporozoite invasion in the mosquito and mammalian hosts.

Plasmodium sporozoites that are transmitted by blood-feeding female Anopheles mosquitoes invade hepatocytes for an initial round of intracellular replication, leading to the release of merozoites that invade and multiply within red blood cells. Sporozoites and merozoites share a number of proteins t...

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Bibliographic Details
Main Authors: Priyanka Fernandes, Manon Loubens, Rémi Le Borgne, Carine Marinach, Béatrice Ardin, Sylvie Briquet, Laetitia Vincensini, Soumia Hamada, Bénédicte Hoareau-Coudert, Jean-Marc Verbavatz, Allon Weiner, Olivier Silvie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-06-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010643

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https://doi.org/10.1371/journal.ppat.1010643

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