Nanoscale metal-organic frameworks for the delivery of nucleic acids to cancer cells

Nanoscale metal-organic frameworks for the delivery of nucleic acids to cancer cells

Therapeutic nucleic acids (TNAs) are gaining increasing interest in the treatment of severe diseases including viral infections, inherited disorders, and cancers. However, the efficacy of intracellularly functioning TNAs is also reliant upon their delivery into the cellular environment, as unmodifie...

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Bibliographic Details
Main Authors: Xue Li, Morgan Chandler, Yelixza I. Avila, Sandra I. Arroyo-Becker, Gilles Patriarche, Antonio Vargas-Berenguel, Juan M. Casas-Solvas, Kirill A. Afonin, Ruxandra Gref
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:International Journal of Pharmaceutics: X
Subjects:
Nanoscale metal-organic frameworks
Drug incorporation
Therapeutic nucleic acids
Surface engineering
Intracellular drug delivery
Online Access:http://www.sciencedirect.com/science/article/pii/S2590156723000051

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http://www.sciencedirect.com/science/article/pii/S2590156723000051

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