CASK Silence Overcomes Sorafenib Resistance of Hepatocellular Carcinoma Through Activating Apoptosis and Autophagic Cell Death

CASK Silence Overcomes Sorafenib Resistance of Hepatocellular Carcinoma Through Activating Apoptosis and Autophagic Cell Death

Hepatocellular carcinoma (HCC) patients usually fail to be treated because of drug resistance, including sorafenib. In this study, the effects of CASK in HCC were investigated using gain- or loss-of-function strategies by performing cell counting kit-8 assay, colony formation assay, flow cytometry,...

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Bibliographic Details
Main Authors: Bisha Ding, Chang Bao, Luqi Jin, Liang Xu, Weimin Fan, Weiyang Lou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
autophagy
apoptosis
HCC
CASK
sorafenib resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.681683/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.681683/full

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