Pyridoxal 5′-Phosphate Biosynthesis by Pyridox-(am)-ine 5′-Phosphate Oxidase: Species-Specific Features

Pyridoxal 5′-Phosphate Biosynthesis by Pyridox-(am)-ine 5′-Phosphate Oxidase: Species-Specific Features

Enzymes reliant on pyridoxal 5′-phosphate (PLP), the metabolically active form of vitamin B<sub>6</sub>, hold significant importance in both biology and medicine. They facilitate various biochemical reactions, particularly in amino acid and neurotransmitter metabolisms. Vitamin B<sub&...

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Bibliographic Details
Main Authors: Maribel Rivero, Nerea Novo, Milagros Medina
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
pyridox-(am)-ine 5′-phosphate oxidase (PNPOx)
pyridoxal 5′-phosphate (PLP)
flavin mononucleotide
species-specific features
conformational landscape
cofactor channelling
Online Access:https://www.mdpi.com/1422-0067/25/6/3174

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https://www.mdpi.com/1422-0067/25/6/3174

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