Histone H4 deacetylation plays a critical role in early gene silencing during neuronal apoptosis

<p>Abstract</p> <p>Background</p> <p>Silencing of normal gene expression occurs early in the apoptosis of neurons, well before the cell is committed to the death pathway, and has been extensively characterized in injured retinal ganglion cells. The causative mechanism o...

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Bibliographic Details
Main Authors: Schlamp Cassandra L, Pelzel Heather R, Nickells Robert W
Format: Article
Language:English
Published: BMC 2010-05-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/11/62