Concise Total Syntheses of (+)‐Brefeldin A, Diastereomers and Analogs and Their Biological Activity

Concise Total Syntheses of (+)‐Brefeldin A, Diastereomers and Analogs and Their Biological Activity

Abstract Brefeldin A is an important natural product and biochemical tool with cell‐modulating and other diverse biological activities. To explore its chemical space, a generally applicable strategy for total syntheses of naturally occurring (+)‐brefeldin A (BFA), 2‐epi‐BFA, their diastereomers and...

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Bibliographic Details
Main Authors: Dr. Mikhail K. Klychnikov, Dr. Radek Pohl, Dr. Ivana Císařová, Dr. Miroslav Hájek, Dr. Ullrich Jahn
Format: Article
Language:English
Published: Wiley-VCH 2023-09-01
Series:ChemistryEurope
Subjects:
brefeldin A
Golgi apparatus
macrolactones
natural products
total synthesis
Online Access:https://doi.org/10.1002/ceur.202300030

Internet

https://doi.org/10.1002/ceur.202300030

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