Craniofacial chondrogenesis in organoids from human stem cell-derived neural crest cells

Summary: Knowledge of cell signaling pathways that drive human neural crest differentiation into craniofacial chondrocytes is incomplete, yet essential for using stem cells to regenerate craniomaxillofacial structures. To accelerate translational progress, we developed a differentiation protocol tha...

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Bibliographic Details
Main Authors: Lauren Foltz, Nagashree Avabhrath, Jean-Marc Lanchy, Tyler Levy, Anthony Possemato, Majd Ariss, Bradley Peterson, Mark Grimes
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224008071