Epigenomic analysis reveals a unique DNA methylation program of metastasis-competent circulating tumor cells in colorectal cancer

Epigenomic analysis reveals a unique DNA methylation program of metastasis-competent circulating tumor cells in colorectal cancer

Abstract Circulating tumor cells (CTCs) and epigenetic alterations are involved in the development of metastasis from solid tumors, such as colorectal cancer (CRC). The aim of this study was to characterize the DNA methylation profile of metastasis-competent CTCs in CRC. The DNA methylome of the hum...

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Bibliographic Details
Main Authors: Aida Bao-Caamano, Nicolás Costa-Fraga, Laure Cayrefourcq, María Amalia Jácome, Aitor Rodriguez-Casanova, Laura Muinelo-Romay, Rafael López-López, Catherine Alix-Panabières, Angel Díaz-Lagares
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-42037-w

Internet

https://doi.org/10.1038/s41598-023-42037-w

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