Skeletal muscle fibers produce B-cell stimulatory factors in chronic myositis

Skeletal muscle fibers produce B-cell stimulatory factors in chronic myositis

IntroductionWe aimed to identify B-cell-mediated immunomechanisms in inclusion body myositis (IBM) and polymyositis (PM) as part of the complex pathophysiology.Materials and methodsHuman primary myotube cultures were derived from orthopedic surgery. Diagnostic biopsy specimens from patients with IBM...

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Bibliographic Details
Main Authors: Per-Ole Carstens, Luisa M. Müllar, Arne Wrede, Sabrina Zechel, Martin M. Wachowski, Almuth Brandis, Sabine Krause, Stephan Zierz, Jens Schmidt
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
autoimmune diseases
neuromuscular disease
inflammatory muscle disease
myositis
B cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1177721/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1177721/full

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