A-to-I RNA editing enzyme ADAR2 regulates light-induced circadian phase-shift

A-to-I RNA editing enzyme ADAR2 regulates light-induced circadian phase-shift

Abstract In mammals, the central circadian clock is located in the suprachiasmatic nucleus (SCN) of the hypothalamus and it orchestrates peripheral clocks in the whole body to organize physiological and behavioral rhythms. Light-induced phase-shift of the SCN clock enables synchronization of the cir...

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Bibliographic Details
Main Authors: Hideki Terajima, Hikari Yoshitane, Tomoko Yoshikawa, Yasufumi Shigeyoshi, Yoshitaka Fukada
Format: Article
Language:English
Published: Nature Portfolio 2018-10-01
Series:Scientific Reports
Subjects:
Pituitary Adenylyl Cyclase-activating Polypeptide (PACAP)
ADAR2 Knockout Mice
Bioluminescence Rhythm
Light-induced Phase Advances
mRNA Rhythm
Online Access:https://doi.org/10.1038/s41598-018-33114-6

Internet

https://doi.org/10.1038/s41598-018-33114-6

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