Mycobacterial Infection of Precision-Cut Lung Slices Reveals Type 1 Interferon Pathway Is Locally Induced by Mycobacterium bovis but Not M. tuberculosis in a Cattle Breed

Mycobacterial Infection of Precision-Cut Lung Slices Reveals Type 1 Interferon Pathway Is Locally Induced by Mycobacterium bovis but Not M. tuberculosis in a Cattle Breed

Tuberculosis exacts a terrible toll on human and animal health. While Mycobacterium tuberculosis (Mtb) is restricted to humans, Mycobacterium bovis (Mb) is present in a large range of mammalian hosts. In cattle, bovine TB (bTB) is a noticeable disease responsible for important economic losses in dev...

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Bibliographic Details
Main Authors: Aude Remot, Florence Carreras, Anthony Coupé, Émilie Doz-Deblauwe, Maria L. Boschiroli, John A. Browne, Quentin Marquant, Delphyne Descamps, Fabienne Archer, Abraham Aseffa, Pierre Germon, Stephen V. Gordon, Nathalie Winter
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Veterinary Science
Subjects:
cattle
Mycobacterium bovis
ex vivo
precision cut lung slices
alveolar macrophages
type I interferon
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2021.696525/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2021.696525/full

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