A novel and cost-effective method for high-throughput 3D culturing and rhythmic assessment of hiPSC-derived cardiomyocytes using retroreflective Janus microparticles

A novel and cost-effective method for high-throughput 3D culturing and rhythmic assessment of hiPSC-derived cardiomyocytes using retroreflective Janus microparticles

Abstract Background Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) gain attention as a potent cell source in regenerative medicine and drug discovery. With the necessity of the demands for experimental models to create a more physiologically relevant model of the heart in vit...

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Bibliographic Details
Main Authors: Huyen T. M. Pham, Duc Long Nguyen, Hyo-Sop Kim, Eun Kyeong Yang, Jae-Ho Kim, Hyun C. Yoon, Hyun-Ji Park
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2023-08-01
Series:Biomaterials Research
Subjects:
3D cell culture platform
hiPSC-CM
Retroreflective Janus microparticle (RJP)
Cardiac rhythm assessment
Online Access:https://doi.org/10.1186/s40824-023-00416-4

Internet

https://doi.org/10.1186/s40824-023-00416-4

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