Toxic effect window of ovarian development in female offspring mice induced by prenatal prednisone exposure with different doses and time

Toxic effect window of ovarian development in female offspring mice induced by prenatal prednisone exposure with different doses and time

Abstract Background Prednisone is one of the most used synthetic glucocorticoids during pregnancy. Epidemiological investigations suggested that prenatal prednisone therapy could affect fetal development, but systematic studies on its effects on ovarian development and the “toxic effect window” rema...

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Bibliographic Details
Main Authors: Jing Huang, Tiancheng Wu, Yating Li, Yuanzhen Zhang, Xingjiang Yu, Dan Xu, Hui Wang
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Journal of Ovarian Research
Subjects:
Prednisone
Prenatal exposure
Ovarian developmental toxicity
Pre-granulosa cell
Oocyte
Online Access:https://doi.org/10.1186/s13048-023-01148-8

Internet

https://doi.org/10.1186/s13048-023-01148-8

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