Methotrexate Treatment Suppresses Monocytes in Nonresponders to Pneumococcal Conjugate Vaccine in Rheumatoid Arthritis Patients

Patients with rheumatoid arthritis (RA) have an increased risk of infections; therefore, immunization against vaccine-preventable diseases is important. Methotrexate (MTX) impairs the antibody response to pneumococcal conjugate vaccine (PCV) in patients with arthritis, and the underlying mechanism i...

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Bibliographic Details
Main Authors: Evelina Elmér, Per Nived, Åsa Pettersson, Lillemor Skattum, Thomas Hellmark, Meliha C. Kapetanovic, Åsa C. M. Johansson
Format: Article
Language:English
Published: Hindawi Limited 2022-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2022/7561661