Enhancing the prediction of protein pairings between interacting families using orthology information

<p>Abstract</p> <p>Background</p> <p>It has repeatedly been shown that interacting protein families tend to have similar phylogenetic trees. These similarities can be used to predicting the mapping between two families of interacting proteins (i.e. which proteins from o...

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Bibliographic Details
Main Authors: Pazos Florencio, Pons Carles, Juan David, Izarzugaza Jose MG, Valencia Alfonso
Format: Article
Language:English
Published: BMC 2008-01-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/9/35