Demonstration of intracellular real-time molecular quantification via FRET-enhanced optical microcavity

The authors introduce an active-mode optical microcavity sensor with enhanced sensitivity via Förster resonant energy transfer. Changes in lasing wavelengths of both donor and acceptor enable quantitative molecular analysis and real-time monitoring of intracellular molecules.

Bibliographic Details
Main Authors: Yaping Wang, Marion C. Lang, Jinsong Lu, Mingqian Suo, Mengcong Du, Yubin Hou, Xiu-Hong Wang, Pu Wang
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34547-4