A comparative study of fat storage quantitation in nematode Caenorhabditis elegans using label and label-free methods.

The nematode Caenorhabditis elegans has been employed as a model organism to study human obesity due to the conservation of the pathways that regulate energy metabolism. To assay for fat storage in C. elegans, a number of fat-soluble dyes have been employed including BODIPY, Nile Red, Oil Red O, and...

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Bibliographic Details
Main Authors: Kelvin Yen, Thuc T Le, Ankita Bansal, Sri Devi Narasimhan, Ji-Xin Cheng, Heidi A Tissenbaum
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2940797?pdf=render