The Role of the Gut Microbiota in the Effects of Early-Life Stress and Dietary Fatty Acids on Later-Life Central and Metabolic Outcomes in Mice

The Role of the Gut Microbiota in the Effects of Early-Life Stress and Dietary Fatty Acids on Later-Life Central and Metabolic Outcomes in Mice

ABSTRACT Early-life stress (ELS) leads to increased vulnerability for mental and metabolic disorders. We have previously shown that a low dietary ω-6/ω-3 polyunsaturated fatty acid (PUFA) ratio protects against ELS-induced cognitive impairments. Due to the importance of the gut microbiota as a deter...

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Bibliographic Details
Main Authors: Kitty Reemst, Sebastian Tims, Kit-Yi Yam, Mona Mischke, Jan Knol, Stanley Brul, Lidewij Schipper, Aniko Korosi
Format: Article
Language:English
Published: American Society for Microbiology 2022-06-01
Series:mSystems
Subjects:
early-life stress
diet
interventions
polyunsaturated fatty acids
microbiota
microbiome
Online Access:https://journals.asm.org/doi/10.1128/msystems.00180-22

Internet

https://journals.asm.org/doi/10.1128/msystems.00180-22

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