Oxidation resistance 1 functions in the maintenance of cellular survival and genome stability in response to oxidative stress-independent DNA damage

Abstract Background DNA damage is generated by various intrinsic and extrinsic sources such as reactive oxygen species (ROS) and environmental mutagens, and causes genomic alterations. DNA damage response (DDR) is activated to induce cell cycle arrest and DNA repair. Oxidation resistance 1 (OXR1) is...

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Bibliographic Details
Main Authors: Ako Matsui, Kazunari Hashiguchi, Masao Suzuki, Qiu-Mei Zhang-Akiyama
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Genes and Environment
Subjects:
Online Access:http://link.springer.com/article/10.1186/s41021-020-00168-w