Study of Different Crystal Habits of Aprepitant: Dissolution and Material Attributes

Study of Different Crystal Habits of Aprepitant: Dissolution and Material Attributes

In the present study, aprepitant (APT) was selected to find its suitable crystal habit, which can improve its existing poor dissolution and manufacturing processability. Solvents were screened out for solubility analysis of APT and further crystal habit modification. Solid-state characterization stu...

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Bibliographic Details
Main Authors: Satyajit R. Datir, Dinesh Kumar, Pradeep Kumar, Sanyog Jain, Arvind Kumar Bansal, Bhargavi Nallamothu, Samarth D. Thakore, Mrudula H. Bele
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Applied Sciences
Subjects:
crystal habit
crystal shape
polymorph
recrystallization
flow characterization
Heckel plot
Online Access:https://www.mdpi.com/2076-3417/11/12/5604

Internet

https://www.mdpi.com/2076-3417/11/12/5604

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