TRAP1 S-nitrosylation as a model of population-shift mechanism to study the effects of nitric oxide on redox-sensitive oncoproteins

Abstract S-nitrosylation is a post-translational modification in which nitric oxide (NO) binds to the thiol group of cysteine, generating an S-nitrosothiol (SNO) adduct. S-nitrosylation has different physiological roles, and its alteration has also been linked to a growing list of pathologies, inclu...

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Bibliographic Details
Main Authors: Elena Papaleo, Matteo Tiberti, Matteo Arnaudi, Chiara Pecorari, Fiorella Faienza, Lisa Cantwell, Kristine Degn, Francesca Pacello, Andrea Battistoni, Matteo Lambrughi, Giuseppe Filomeni
Format: Article
Language:English
Published: Nature Publishing Group 2023-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05780-6